Avhandlingar och publikationer

Coeliac disease in children and adolescents with type 1 diabetes – Screening, diagnosis and prevalence

Publicerad 9 september 2020

Coeliac disease in children and adolescents with type 1 diabetes – Screening, diagnosis and prevalence Mara Cerqueiro Bybrant, Department of Women’s and Children’s Health Karolinska Institutet, Stockholm, Sweden, 2020

Coeliac disease (CD) is more common in children and adolescents with type 1 diabetes (T1D). Both diseases share the same high-risk genes: human leukocyte antigen (HLA) DQ2 and DQ8. Other factors than gluten intake and high-risk genes are necessary to develop CD. In Sweden, there was a dramatic increase in CD in young, otherwise healthy, children between 1984 and 1996 and this has been called the “Swedish epidemic of coeliac disease”, hereinafter referred as the Swedish CD epidemic. Over the last decade, the diagnostic guidelines for CD in children and adolescents have changed, but children with T1D are still not included in protocols to determine CD diagnosis without a biopsy, due to a lack of data.

Thesis Coeliac Disease in children and adolescents with type 1 diabetes Mara Cerqueiro Bybrant 2020 (pdf)